Ed Seto, PhD
Associate Center Director for Basic Sciences at the GW Cancer Center
Professor in the Department of Biochemistry & Molecular Medicine at GW School of Medicine & Health Sciences
Seto received his bachelorʼs degree from the University of California at Irvine, and his PhD from the University of California at San Francisco. After completing an American Cancer Society Postdoctoral Fellowship at Princeton University, Dr. Seto spent four years as an assistant professor at the University of Texas before moving his research group to the Moffitt Cancer Center at the University of South Florida.
Lei Sun, PhD
Lei Sun completed her PhD from the Nankai University of Cell Biology and Genetics in China. Currently, her research focuses on the functional role of HDAC11 in switching genes on and off, as well as related molecular mechanisms in metabolism.
Yixuan Li, PhD
Yixuan Li received her doctoral degree from Tianjin Medical School in China. As a postdoctoral fellow, her work has focused on exploring the epigenetic mechanism in cancer. Epigenetic regulations via histone acetylation, DNA methylation, as well as by microRNAs (miRNAs) have been implicated in cancer development and progression. Her major interest is to define the role of HDACs in regulating the malignant phenotype of tumor cells.
Ka Bian, PhD
Associate Research Professor
Ka Bian received his PhD from Shiga University of Medical Sciences in Japan. Previously, he studied the role of nitric-oxide cyclic GMP signaling in the realm of cancer biology. After joining the Seto lab, he sought to examine HDACs regulation of nitric oxide-cyclic GMP signaling, and its potential use in cancer therapy.
Lirong Peng, PhD
Assistant Research Professor
After completing her doctoral degree in the Peking University School of Oncology in China, Lirong Peng joined the Seto lab. Her interest is in exploring the biological and functional roles of Class III HDACs and their related molecular mechanisms in human disease. Specifically, she is examining the roles of Sirt1 in DNA damage pathways.
Hongbo Ling, PhD
Hongbo Ling completed his doctorate in Genetics from the Institute of Microbiology at the Chinese Academy of Sciences in Beijing, China. With an interest in the family of HDACs, his research is focused on the role of HDACs in carcinogenesis and their underlying mechanisms.
Irene Santos Barriopedro, PhD
Irene Santos Barriopedro received her doctorate in Biomedicine from the University of Barcelona, in Spain. She moved to DC and joined the Seto lab to study her interest in HDAC8. Her research focuses on HDAC8’s substrates and binding proteins, as well as their roles in various cellular pathways.
Eden Dejene is a PhD candidate in the Molecular Medicine program with a specialization in molecular and cellular oncology. Currently, she is studying the relationship between histone deacetylases and microRNAs in cancer regulation.
Sonali Bahl is a PhD candidate in the Molecular Medicine program with a specialization in molecular and cellular oncology. She is investigating the role of tyrosine phosphorylation, in relation to histone deacteylases.
Raneen Rahhal, M.S.
Senior Research Assistant/Lab Manager
Raneen Rahhal received her Master’s in Tumor Biology at Georgetown University. Her research is focused on understanding the regulation of HDACs, and its effect in metabolic pathways.